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KMID : 0616120000310030345
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Korean Journal of Pharmacognosy
2000 Volume.31 No. 3 p.345 ~ p.350
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Physicochemical and Biological Characteristics of Flavonoids Isolated from the Heartwoods of Rhus verniciflua
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Park Hee-Juhn
Kwon Sang-Hyuk
Kim Gap-Tae
Lee Kyung-Tae
Choi Jung-Hye
Choi Jong-Won
Park Kun-Young
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Abstract
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From the heartwood of Rhus verniciflua, four known flavonoids (1-4) were isolated along with an unknown one (5). Compounds 1-4 were identified to be garbanzol, sulfuretin, fisetin and fustin by NMR data. NMR data of 1-4 were fully assigned by the aids of 2D-NMR spectra. Among these compounds, only sulfuretin had significant cytotoxic and antioxidant ability at high concentrations. In addition, it seems likely that the 5-hydroxy-lacking flavonoids could not influence on the activity of laccase with cofactor of cupric cation, which catalyzes oxidative coupling reaction, in this plant.
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KEYWORD
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Rhus verniciflua, Anacardiaceae, flavonids, sulfuretin, antioxidant, cytotoxic, NMR
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